NUP98 抗体 (AA 728-1787) (Fluoro647)
Our Local Distributor
北京 101111
Quick Overview for NUP98 抗体 (AA 728-1787) (Fluoro647) (ABIN8017441)
抗原
See all NUP98 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 728-1787
-
原理
- Anti-NUP98 Antibody Fluoro647 Conjugated
-
交叉反应 (详细)
- No cross reactivity with other proteins.
-
预测反应
- Human NUP98 shares 89.1%,89% amino acid (aa) sequence identity with mouse,rat NUP98,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human NUP98 recombinant protein (Position: H728-I1787). Human NUP98 shares 89.1% and 89% amino acid (aa) sequence identity with mouse and rat NUP98, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- NUP98 (Nucleoporin 98kDa (NUP98))
-
别名
- NUP98
-
背景
-
Background: Nuclear pore complex protein Nup98-Nup96 is a protein that in humans is encoded by the NUP98 gene. This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. NUP98 is a peripheral nucleoporin located at both the cytoplasmic and nuclear sides of the central channel of the NPC. NUP98 phosphorylation is critical for NPC disassembly at the onset of mitosis. It also plays roles in gene expression, mitotic checkpoint, and pathogenesis. Ligand blot analysis suggested that NUP98 can function as a docking protein for cytosol-mediated docking of import substrates. In addition to that, NUP98 is a target of the vesicular stomatitis virus M protein-mediated inhibition of mRNA nuclear export.
Gene Full Name: nucleoporin 98 and 96 precursor
-
基因ID
- 4928
-
UniProt
- P52948
-
途径
- Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
抗原
-