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NUP98 抗体 (AA 549-880) (Fluoro550)

This 兔 多克隆 antibody specifically detects NUP98 in FACS. It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN8017424
发货至: 中国
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Quick Overview for NUP98 抗体 (AA 549-880) (Fluoro550) (ABIN8017424)

抗原

See all NUP98 抗体
NUP98 (Nucleoporin 98kDa (NUP98))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

  • 60
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多克隆

标记

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This NUP98 antibody is conjugated to Fluoro550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 549-880

    原理

    Anti-NUP98 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human NUP98 shares 95%,94% amino acid (aa) sequence identity with mouse,rat NUP98,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NUP98 recombinant protein (Position: H549-F880). Human NUP98 shares 95% and 94% amino acid (aa) sequence identity with mouse and rat NUP98, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    NUP98 (Nucleoporin 98kDa (NUP98))

    别名

    NUP98

    背景

    Background: Nuclear pore complex protein Nup98-Nup96 is a protein that in humans is encoded by the NUP98 gene. This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. NUP98 is a peripheral nucleoporin located at both the cytoplasmic and nuclear sides of the central channel of the NPC. NUP98 phosphorylation is critical for NPC disassembly at the onset of mitosis. It also plays roles in gene expression, mitotic checkpoint, and pathogenesis. Ligand blot analysis suggested that NUP98 can function as a docking protein for cytosol-mediated docking of import substrates. In addition to that, NUP98 is a target of the vesicular stomatitis virus M protein-mediated inhibition of mRNA nuclear export.

    Gene Full Name: nucleoporin 98 and 96 precursor

    Sequence Similarities: Belongs to the nucleoporin GLFG family.

    基因ID

    4928

    UniProt

    P52948

    途径

    Stem Cell Maintenance, Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome
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