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NPM1 抗体 (N-Term) (FITC)

The 兔 多克隆 anti-NPM1 antibody is suitable to detect NPM1 in samples from 人, 小鼠, 大鼠 和 猴. It has been validated for FACS.
产品编号 ABIN8017227
发货至: 中国
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Room 801-803
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Quick Overview for NPM1 抗体 (N-Term) (FITC) (ABIN8017227)

抗原

See all NPM1 抗体
NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

适用

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人, 小鼠, 大鼠, 猴

宿主

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克隆类型

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多克隆

标记

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This NPM1 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
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    N-Term

    原理

    Anti-Nucleophosmin/NPM1 Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related rat,mouse sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Nucleophosmin, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

    别名

    NPM1

    背景

    Background: NPM1 (Nucleophosmin/Nucleoplasmin family, member1), also known as NPM, nucleolar phosphoprotein B23 or numatrin, is a protein that in humans is encoded by the NPM1 gene. The NPM1 gene maps to chromosome 5q35. Chan et al. (1989) found that nucleophosmin is a nucleolar phosphoprotein that is more abundant in tumor cells than in normal resting cells. Stimulation of the growth of normal cells, e.g., mitogen activation of B lymphocytes, was accompanied by an increase in nucleophosmin protein level. They stated that nucleophosmin is likely involved in the assembly of ribosomal proteins into ribosomes. Electron microscopic study indicated that nucleophosmin is concentrated in the granular region of the nucleolus, where ribosome assembly occurs.

    Gene Full Name: nucleophosmin 1

    Sequence Similarities: Belongs to the nucleoplasmin family.

    基因ID

    4869

    UniProt

    P06748

    途径

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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