GOT1 抗体 (AA 301-400)
Quick Overview for GOT1 抗体 (AA 301-400) (ABIN752008)
抗原
See all GOT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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特异性
- This antibody is specific for cytoplasmic Aspartate Aminotransferase, and will not detect the mitochondrial form.
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Aspartate aminotransferase, cytoplasmic
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))
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别名
- Aspartate Aminotransferase, Cytoplasmic
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背景
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Synonyms: cCAT, GIG18, cAspAT, ASTQTL1, Aspartate aminotransferase, cytoplasmic, Cysteine aminotransferase, cytoplasmic, Cysteine transaminase, cytoplasmic, Glutamate oxaloacetate transaminase 1, Transaminase A, GOT1
Background: Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
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基因ID
- 2805
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UniProt
- P17174
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途径
- Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process
抗原
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