NCOA1 抗体 (AA 614-826) (Fluoro488)
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Quick Overview for NCOA1 抗体 (AA 614-826) (Fluoro488) (ABIN8016784)
抗原
See all NCOA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 614-826
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原理
- Anti-KAT13A/SRC1/NCOA1 Antibody Fluoro488 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human KAT13A shares 92% amino acid (aa) sequence identity with mouse KAT13A.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human KAT13A recombinant protein (Position: H614-Q826). Human KAT13A shares 92% amino acid (aa) sequence identity with mouse KAT13A.
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亚型
- IgG
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anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1222-1441) antibody
NCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 614-826) antibodyNCOA1 适用: 人 WB, FACS, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1338-1367), (C-Term) antibodyNCOA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14368 unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 600-650) antibodyNCOA1 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 201-300) antibodyNCOA1 适用: 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (N-Term) antibodyNCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 594-625) antibodyNCOA1 适用: 人 WB 宿主: 兔 Polyclonal RB14285 unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 284-393) antibodyNCOA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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别名
- NCOA1
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背景
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Background: The nuclear receptor coactivator 1 (NCOA1), also known as SRC1, is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity. NCOA1 is recruited to DNA promotion sites by ligand-activated nuclear receptors. NCOA1, in turn, acylates histones, which makes downsteam DNA more accessible to transcription. Hence, NCOA1 assists nuclear receptors in the upregulation of DNA expression. It has been found that NCOA1 can enhance the transcriptional activity of ligand-bound PGR but does not alter the basal activity of the target promoter. It also enhances estrogen receptor, glucocorticoid receptor, thyroid hormone receptor, and retinoid X receptor transcriptional activities through their cognate DNA response elements in the presence of hormone. What's more, SRC1 may play a role as a bridging molecule between nuclear hormone receptors and general transcription factors.
Gene Full Name: nuclear receptor coactivator 1
Sequence Similarities: Belongs to the SRC/p160 nuclear receptor coactivator family.
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基因ID
- 8648
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UniProt
- Q15788
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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