NPLOC4 抗体 (AA 1-495) (Fluoro647)
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北京 101111
Quick Overview for NPLOC4 抗体 (AA 1-495) (Fluoro647) (ABIN8016714)
抗原
See all NPLOC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-495
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原理
- Anti-NPL4/NPLOC4 Antibody Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NPL4/NPLOC4 recombinant protein (Position: M1-N495).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
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别名
- NPLOC4
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背景
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Background: Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene. Nuclear protein localization protein 4 (NPL4, NPLOC4) was originally identified as a yeast nuclear transport protein that was later recognized as a critical component of the endoplasmic reticulum-associated degradation (ERAD) pathway. Mammalian NPL4 protein has an amino-terminal ubiquitin-like domain containing a p97 binding site, and a conserved carboxy-terminal zinc finger (NZF) motif responsible for binding ubiquitinated target proteins. NPL4 binds ubiquitin fusion degradation protein 1 (UFD1) to form a heterodimer that associates with the p97 AAA-ATPase, creating a protein complex that mediates delivery of ubiquitinated ER proteins to the proteasome.
Gene Full Name: NPL4 homolog, ubiquitin recognition factor
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基因ID
- 55666
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UniProt
- Q8TAT6
抗原
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