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NPLOC4 抗体 (AA 1-495) (HRP)

The 兔 多克隆 anti-NPLOC4 antibody is suitable to detect NPLOC4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC.
产品编号 ABIN8016711
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NPLOC4 抗体 (AA 1-495) (HRP) (ABIN8016711)

抗原

See all NPLOC4 抗体
NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

适用

  • 32
  • 17
  • 15
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 2

克隆类型

  • 34
多克隆

标记

  • 20
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NPLOC4 antibody is conjugated to HRP

应用范围

  • 23
  • 14
  • 8
  • 6
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 11
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-495

    原理

    Anti-NPL4/NPLOC4 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NPL4/NPLOC4 recombinant protein (Position: M1-N495).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

    别名

    NPLOC4

    背景

    Background: Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene. Nuclear protein localization protein 4 (NPL4, NPLOC4) was originally identified as a yeast nuclear transport protein that was later recognized as a critical component of the endoplasmic reticulum-associated degradation (ERAD) pathway. Mammalian NPL4 protein has an amino-terminal ubiquitin-like domain containing a p97 binding site, and a conserved carboxy-terminal zinc finger (NZF) motif responsible for binding ubiquitinated target proteins. NPL4 binds ubiquitin fusion degradation protein 1 (UFD1) to form a heterodimer that associates with the p97 AAA-ATPase, creating a protein complex that mediates delivery of ubiquitinated ER proteins to the proteasome.

    Gene Full Name: NPL4 homolog, ubiquitin recognition factor

    基因ID

    55666

    UniProt

    Q8TAT6
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