NFIB 抗体 (Middle Region) (FITC)
Our Local Distributor
北京 101111
Quick Overview for NFIB 抗体 (Middle Region) (FITC) (ABIN8016391)
抗原
See all NFIB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- Middle Region
-
原理
- Anti-NFIB/NF1B2 Antibody (monoclonal, 4D6E4) FITC Conjugated
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
预测反应
- identical to the related mouse,rat sequences.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human NFIB/NF1B2, identical to the related mouse and rat sequences.
-
亚型
- IgG2b
-
-
anti-Nuclear Factor I/B (NFIB) (AA 1-420) antibody
NFIB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Nuclear Factor I/B (NFIB) antibodyNFIB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor I/B (NFIB) (Middle Region) antibodyNFIB 适用: 人, 小鼠, 大鼠 WB, FACS, ICC, IF 宿主: 小鼠 Monoclonal 4D6E4 unconjugated
anti-Nuclear Factor I/B (NFIB) (Middle Region) antibodyNFIB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor I/B (NFIB) (AA 1-420) antibodyNFIB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Factor I/B (NFIB) (AA 255-283) antibodyNFIB 适用: 人 WB 宿主: 兔 Polyclonal RB36790 unconjugated
anti-Nuclear Factor I/B (NFIB) antibodyNFIB 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB3600 unconjugated Recombinant Antibody
anti-Nuclear Factor I/B (NFIB) (AA 1-233) antibodyNFIB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor I/B (NFIB) (AA 187-236) antibodyNFIB 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 绵羊, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Factor I/B (NFIB) antibodyNFIB 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- NFIB (Nuclear Factor I/B (NFIB))
-
别名
- NFIB
-
背景
-
Background: Nuclear factor 1 B-type is a protein that in humans is encoded by the NFIB gene. The NFIB gene is a part of the NFI gene complex that includes three other genes (NFIA, NFIC and NFIX). The NFIB gene is a protein coding gene that also serves as a transcription factor. This gene is essential in embryonic development and it works together with its gene complex to initiate tissue differentiation in the fetus. Through knockout experiments, researchers found that mice without the NFIB gene have severely underdeveloped lungs. This mutation does not seem to cause spontaneous abortions because in utero the fetus does not use its lungs for respiration. However, this becomes lethal once the fetus is born and has to take its first breath. It is thought that NFIB plays a role in down regulating the transcription factors TGF-β1 and Shh in normal gestation because they remained high in knockout experiments. The absence of NFIB also leads to insufficient amounts of surfactant being produced which is one reason why the mice cannot breathe once it is born. The knockout experiments demonstrated that NFIB has a significant role in fore-brain development. NFIB is typically found in pontine nuclei of the CNS, the cerebral cortex and the white matter of the brain and without NFIB these areas are dramatically affected.
Gene Full Name: nuclear factor I B
-
基因ID
- 4781
-
UniProt
- O00712
抗原
-
