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NLRP2 抗体 (AA 80-1044) (Cy3)

This 兔 多克隆 antibody specifically detects NLRP2 in FACS. It exhibits reactivity toward 人.
产品编号 ABIN8015858
发货至: 中国
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Quick Overview for NLRP2 抗体 (AA 80-1044) (Cy3) (ABIN8015858)

抗原

See all NLRP2 抗体
NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

适用

  • 57
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宿主

  • 51
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克隆类型

  • 52
  • 6
多克隆

标记

  • 39
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This NLRP2 antibody is conjugated to Cy3

应用范围

  • 40
  • 19
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  • 10
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Flow Cytometry (FACS)
  • 抗原表位

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    AA 80-1044

    原理

    Anti-NLRP2 Antibody Cy3 Conjugated

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NLRP2 recombinant protein (Position: H80-D1044).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

    别名

    NLRP2

    背景

    Background: NACHT, LRR and PYD domains-containing protein 2 is a protein that in humans is encoded by the NLRP2 gene. This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Gene Full Name: NLR family pyrin domain containing 2

    基因ID

    55655

    UniProt

    Q9NX02

    途径

    Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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