NK2 Homeobox 5 抗体 (AA 15-132)
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Quick Overview for NK2 Homeobox 5 抗体 (AA 15-132) (ABIN8015790)
抗原
See all NK2 Homeobox 5 (NKX2-5) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 15-132
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原理
- Anti-Nkx2.5/NKX2-5 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Nkx2.5/NKX2-5 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Nkx2.5/NKX2-5 recombinant protein (Position: K15-R132).
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亚型
- IgG
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- NK2 Homeobox 5 (NKX2-5)
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别名
- NKX2-5
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背景
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Background: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 ly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.
Gene Full Name: NK2 homeobox 5
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分子量
- 35 kDa
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基因ID
- 1482
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UniProt
- P52952
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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