NK2 Homeobox 5 抗体 (AA 15-132) (HRP)
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Quick Overview for NK2 Homeobox 5 抗体 (AA 15-132) (HRP) (ABIN8015786)
抗原
See all NK2 Homeobox 5 (NKX2-5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-132
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原理
- Anti-Nkx2.5/NKX2-5 Antibody HRP Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Nkx2.5/NKX2-5 recombinant protein (Position: K15-R132).
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- NK2 Homeobox 5 (NKX2-5)
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别名
- NKX2-5
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背景
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Background: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 ly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.
Gene Full Name: NK2 homeobox 5
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基因ID
- 1482
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UniProt
- P52952
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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