NRP2 抗体 (N-Term) (HRP)
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北京 101111
Quick Overview for NRP2 抗体 (N-Term) (HRP) (ABIN8015115)
抗原
See all NRP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Neuropilin-2 NRP2 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related mouse sequence,different from the related rat sequence by one amino acid.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human NRP2, identical to the related mouse sequence and different from the related rat sequence by one amino acid.
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亚型
- IgG
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anti-Neuropilin 2 (NRP2) (AA 231-490) antibody
NRP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 150-420) antibodyNRP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) antibodyNRP2 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 60-209) antibodyNRP2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 621-715) antibodyNRP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Neuropilin 2 (NRP2) (N-Term) antibodyNRP2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) antibodyNRP2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 798-827), (C-Term) antibodyNRP2 适用: 人 WB 宿主: 兔 Polyclonal RB19998 unconjugated
anti-Neuropilin 2 (NRP2) (AA 747-758), (Extracellular), (N-Term) antibodyNRP2 适用: 人 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Neuropilin 2 (NRP2) (AA 621-715) antibodyNRP2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- NRP2 (Neuropilin 2 (NRP2))
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别名
- NRP2
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背景
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Background: NRP2 (Neuropilin-2), also called Npn2 or VEGF165R2, encodes a member of the neuropilin family of receptor proteins. The soluble NRP2 was secreted as a 62.5-kD protein following transfection in Chinese hamster ovary cells. The NRP2 gene is mapped on 2q33.3. The NRP2 gene contains 17 exons and spans about 112 kb. Sema3b can act to repulse axons expressing neuropilin-2 and can antagonize the repulsive action of Sema3a on axonal growth cones expressing neuropilin-1. This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Mice with null mutations in genes encoding Sema3F, and its holoreceptor components Npn2 and plexin A3 (PLEXA3), exhibit increased dentate gyrus granule cell and cortical layer V pyramidal neuron spine number and size, and also aberrant spine distribution. Moreover, Sema3F promotes loss of spines and excitatory synapses in dissociated neurons in vitro, and in Npn2-null brain slices cortical layer V and dentate gyrus granule cells exhibit increased miniature excitatory postsynaptic current frequency. These disparate effects of secreted semaphorins are reflected in the restricted dendritic localization of Npn2 to apical dendrites and of Npn1 to all dendrites of cortical pyramidal neurons.
Gene Full Name: neuropilin 2
Sequence Similarities: Belongs to the neuropilin family.
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基因ID
- 8828
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UniProt
- O60462
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途径
- Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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