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Neuropilin 1 抗体 (AA 504-827) (HRP)

The 小鼠 单克隆 anti-Neuropilin 1 antibody is suitable to detect Neuropilin 1 in samples from 人 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8015082
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Neuropilin 1 抗体 (AA 504-827) (HRP) (ABIN8015082)

抗原

See all Neuropilin 1 (NRP1) 抗体
Neuropilin 1 (NRP1)

适用

  • 188
  • 104
  • 73
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 138
  • 55
  • 13
  • 7
  • 4
小鼠

克隆类型

  • 119
  • 98
单克隆

标记

  • 85
  • 24
  • 20
  • 11
  • 11
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neuropilin 1 antibody is conjugated to HRP

应用范围

  • 124
  • 79
  • 63
  • 40
  • 34
  • 27
  • 24
  • 15
  • 14
  • 13
  • 4
  • 4
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

4G3F7
  • 抗原表位

    • 37
    • 15
    • 13
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 504-827

    原理

    Anti-Neuropilin 1 Antibody (monoclonal, 4G3F7) HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human Neuropilin 1 shares 95%,94% amino acid (aa) sequences identity with mouse,rat Neuropilin 1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Neuropilin 1 recombinant protein (Position: K504-T827). Human Neuropilin 1 shares 95% and 94% amino acid (aa) sequences identity with mouse and rat Neuropilin 1, respectively.

    亚型

    IgG2b
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Neuropilin 1 (NRP1)

    别名

    NRP1

    背景

    Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contain a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

    Gene Full Name: neuropilin 1

    基因ID

    8829

    UniProt

    O14786

    途径

    Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
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