NPBWR1 抗体 (AA 58-328)
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北京 101111
Quick Overview for NPBWR1 抗体 (AA 58-328) (ABIN8015042)
抗原
See all NPBWR1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 58-328
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原理
- Anti-GPCR GPR7/NPBWR1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GPCR GPR7/NPBWR1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GPCR GPR7/NPBWR1 recombinant protein (Position: V58-A328).
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亚型
- IgG
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anti-Neuropeptides B/W Receptor 1 (NPBWR1) (Extracellular Domain) antibody
NPBWR1 适用: 人, 大鼠 IHC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (Cytoplasmic Domain) antibodyNPBWR1 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (C-Term) antibodyNPBWR1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (Cytoplasmic Domain) antibodyNPBWR1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (AA 145-158), (Intracellular), (Loop 2) antibodyNPBWR1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) antibodyNPBWR1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptides B/W Receptor 1 (NPBWR1) (AA 221-250), (C-Term) antibodyNPBWR1 适用: 人 WB 宿主: 兔 Polyclonal RB35592 unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))
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别名
- NPBWR1
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背景
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Background: Neuropeptides B/W receptor 1, also known as NPBW1 and GPR7, is a human protein encoded by the NPBWR1 gene. In rodent models, NPBWR1 is over-expressed in Schwann cells associated with neuropathic pain, suggesting it inhibits inflammatory pain responses. Mice without NPBW1 exhibited a stronger hostile reaction to intruders, suggesting NPBW1 has a role in stress responses. Early studies indicated that NPB and NPW had a complex effect on appetite, but generally led to anorexia. Similarly, male rats lacking NPBWR1 exhibited hyperphagiaand adult-onset obesity, though why female rats are unaffected is unknown. Researchers speculated that activating these pathways might decrease obesity, and synthesized a small-molecule ligand that is capable of stimulating both receptors at low concentrations.
Gene Full Name: neuropeptides B and W receptor 1
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分子量
- 43 kDa
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基因ID
- 2831
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UniProt
- P48145
抗原
-
