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Merlin 抗体 (AA 15-565) (Fluoro594)

The Fluoro594-conjugated 兔 多克隆 anti-Merlin antibody (ABIN8014717) specifically detects Merlin in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8014717
发货至: 中国
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Quick Overview for Merlin 抗体 (AA 15-565) (Fluoro594) (ABIN8014717)

抗原

See all Merlin (NF2) 抗体
Merlin (NF2) (Neurofibromin 2 (NF2))

适用

  • 93
  • 80
  • 71
  • 5
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  • 1
人, 小鼠, 大鼠

宿主

  • 107
  • 4
  • 1

克隆类型

  • 98
  • 14
多克隆

标记

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  • 6
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  • 1
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This Merlin antibody is conjugated to Fluoro594

应用范围

  • 87
  • 37
  • 27
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  • 22
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  • 13
  • 10
  • 6
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  • 3
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 30
    • 15
    • 12
    • 8
    • 6
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    • 2
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    • 2
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    • 1
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-565

    原理

    Anti-NF2/Merlin Antibody Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NF2/Merlin recombinant protein (Position: K15-N565).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Merlin (NF2) (Neurofibromin 2 (NF2))

    别名

    NF2

    背景

    Background: Human merlin is coded by the gene NF2 in Chromosome 22. It is mapped to 22q12.2. This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development, in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

    Gene Full Name: NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

    基因ID

    4771

    UniProt

    P35240

    途径

    Cell-Cell Junction Organization
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