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Neurofibromin 1 抗体 (AA 160-270) (Cy3)

This 小鼠 单克隆 antibody specifically detects Neurofibromin 1 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN8014703
发货至: 中国
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Quick Overview for Neurofibromin 1 抗体 (AA 160-270) (Cy3) (ABIN8014703)

抗原

See all Neurofibromin 1 (NF1) 抗体
Neurofibromin 1 (NF1)

适用

  • 103
  • 77
  • 59
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 88
  • 31
小鼠

克隆类型

  • 86
  • 33
单克隆

标记

  • 38
  • 8
  • 7
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Neurofibromin 1 antibody is conjugated to Cy3

应用范围

  • 39
  • 39
  • 36
  • 35
  • 34
  • 21
  • 17
  • 17
  • 9
  • 9
  • 7
  • 1
Flow Cytometry (FACS)

克隆位点

4F8B7
  • 抗原表位

    • 38
    • 15
    • 15
    • 15
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 160-270

    原理

    Anti-Neurofibromin/NF1 Antibody (monoclonal, 4F8B7) Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Neurofibromin/NF1 recombinant protein (Position: R160-Q270).

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Neurofibromin 1 (NF1)

    别名

    NF1

    背景

    Background: Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

    Gene Full Name: neurofibromin 1

    基因ID

    4763

    UniProt

    P21359

    途径

    cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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