Netrin 3 抗体 (AA 51-473) (Biotin)
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北京 101111
Quick Overview for Netrin 3 抗体 (AA 51-473) (Biotin) (ABIN8014383)
抗原
See all Netrin 3 (Ntn3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-473
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原理
- Anti-NTN3 Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NTN3 recombinant protein (Position: R51-R473).
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亚型
- IgG
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anti-Netrin 3 (Ntn3) (AA 445-458), (Secreted) antibody
Ntn3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Netrin 3 (Ntn3)
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别名
- NTN3
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背景
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Background: Netrins are a family of highly conserved proteins responsible for axon guidance and cell movement throughout neural development. Netrins can be divided into secreted netrins (netrin 1,3,4 and 5) and membrane-tethered glycophosphatidylinositol (GPI)-linked netrins (netrin G1 and G2).Secreted netrins carry their function via interaction with several receptors that include the deleted in colorectal (DCC) family, and the uncoordinated-5 (UNC5-A through UNC5-D) family.Netrin-3 was discovered in 1997 using sequence homology searching of netrin-2. Similarly to other netrins, Netrin-3 plays an important role in the development of the nervous system. Netrin-3 structure consist of a laminin-like domain located on the N-terminal, three epidermal growth factors like repeats (EGF), and a C-terminal netrin-like domain (NTR). Mutations in NTN3, the gene encoding netrin-3 was found to be associated with the development of several carcinomas.
Gene Full Name: netrin 3
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基因ID
- 4917
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UniProt
- O00634
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途径
- Regulation of Muscle Cell Differentiation
抗原
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