Netrin 1 抗体 (N-Term) (HRP)
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Quick Overview for Netrin 1 抗体 (N-Term) (HRP) (ABIN8014378)
抗原
See all Netrin 1 (NTN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Netrin 1/NTN1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Netrin 1, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Netrin 1 (NTN1) (C-Term) antibody
Verified NTN1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 501-604) antibodyNTN1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 小鼠, 人, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 568-596), (C-Term) antibodyNTN1 适用: 人 WB 宿主: 兔 Polyclonal RB44404 unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 小鼠, 人, 大鼠, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (AA 186-478) antibodyNTN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) antibodyMicroarray verified NTN1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB577874 unconjugated
anti-Netrin 1 (NTN1) antibodyMicroarray verified NTN1 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB935839 unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Netrin 1 (NTN1) (C-Term) antibodyNTN1 适用: 小鼠, 人, 大鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Netrin 1 (NTN1)
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别名
- NTN1
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背景
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Background: Netrin-1 (NTN1), also known as NTN1L, is a diffusible protein made by floor plate cells. Netrin-1 is found in the floor plate and neuroepithelial cells of the ventral region of the spinal cord, as well as other locations in the nervous system including the somatic mesoderm, pancreas and cardiac muscle. The human NTN1 gene is mapped to chromosome 17p13-p12 by FISH. Netrin-1 can attract spinal commissural axons and repel trochlear axons in vitro. And netrin-1 expression confers a selective advantage for tumor cell survival. The binding of netrin-1 to DCC appears to depend on the presence of a coreceptor or accessory proteins. Adenosine A2b receptor is actually a netrin-1 receptor and induces cAMP accumulation on binding netrin-1, and that netrin-1-dependent outgrowth of dorsal spinal cord axons ly involves A2b. Netrin-1 can promote intestinal tumor development, probably by regulating cell survival. Thus, a netrin-1 receptor or receptors function as conditional tumor suppressors. Expression of Unc5b triggered endothelial cell repulsion in response to netrin-1 in vitro, whereas a truncated Unc5b lacking the intracellular signaling domain failed to induce repulsion.
Gene Full Name: netrin 1
Sequence Similarities: Contains 3 laminin EGF-like domains.
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基因ID
- 9423
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UniProt
- O95631
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途径
- Regulation of Cell Size
抗原
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