NUB1 抗体 (AA 190-543) (Biotin)
Our Local Distributor
北京 101111
Quick Overview for NUB1 抗体 (AA 190-543) (Biotin) (ABIN8014174)
抗原
See all NUB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 190-543
-
原理
- Anti-NUB1 Antibody Biotin Conjugated
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human NUB1 recombinant protein (Position: K190-D543).
-
亚型
- IgG
-
-
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-326) antibody
NUB1 适用: 人, 猴, 大鼠, 犬 WB, IHC, FACS, IHC (p), IF 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-326) antibodyNUB1 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 87-117), (N-Term) antibodyNUB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2874 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 513-542), (C-Term) antibodyNUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2875 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (C-Term) antibodyNUB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-601) antibodyNUB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB15825 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (C-Term) antibodyNUB1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
-
别名
- NUB1
-
背景
-
Background: NEDD8 µLtimate buster 1 is a protein that in humans is encoded by the NUB1 gene. This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants.
Gene Full Name: negative regulator of ubiquitin like proteins 1
-
基因ID
- 51667
-
UniProt
- Q9Y5A7
抗原
-
