NDFIP2 抗体 (AA 16-336) (Fluoro550)
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北京 101111
Quick Overview for NDFIP2 抗体 (AA 16-336) (Fluoro550) (ABIN8014144)
抗原
See all NDFIP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-336
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原理
- Anti-NDFIP2 Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
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别名
- NDFIP2
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背景
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Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
Gene Full Name: Nedd4 family interacting protein 2
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基因ID
- 54602
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UniProt
- Q9NV92
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途径
- Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
抗原
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