NOXA1 抗体 (Middle Region) (APC)
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北京 101111
Quick Overview for NOXA1 抗体 (Middle Region) (APC) (ABIN8013818)
抗原
See all NOXA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-NOXA1 Antibody APC Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human NOXA1.
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亚型
- IgG
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anti-NADPH Oxidase Activator 1 (NOXA1) (AA 150-313) antibody
NOXA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase Activator 1 (NOXA1) (AA 1-483) antibodyNOXA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase Activator 1 (NOXA1) (AA 301-400) antibodyNOXA1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-NADPH Oxidase Activator 1 (NOXA1) (AA 1-483) antibodyNOXA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-NADPH Oxidase Activator 1 (NOXA1) (AA 449-478), (C-Term) antibodyNOXA1 适用: 人 WB 宿主: 兔 Polyclonal RB24243 unconjugated
anti-NADPH Oxidase Activator 1 (NOXA1) (AA 140-300) antibodyNOXA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NOXA1 (NADPH Oxidase Activator 1 (NOXA1))
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别名
- NOXA1
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背景
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Background: NOXA1 (NADPH oxidase activator 1), also called NOX ACTIVATOR 1 or p51-NOX, is an enzyme that in humans is encoded by the NOXA1 gene. Hartz (2007) mapped the NOXA1 gene to chromosome 9q34.3 based on an alignment of the NOXA1 sequence with the genomic sequence (build 36.1). Banfi et al. (2003) mapped the mouse Noxa1 gene to chromosome 2. Using yeast 2-hybrid assays, Takeya et al. (2003) showed that human p51-NOX interacted with constitutively active forms of RAC1 and RAC2. In vitro binding assays revealed that p51-NOX bound GTP-bound RAC1, but not GDP-bound RAC1. p51-NOX also bound p47-PHOX (NCF1) and p41-NOX (NOXO1), and trp436 within the SH3 domain of p51-NOX was required for these interactions. Human cell lines or COS-7 cells cotransfected with p51-NOX and p41-NOX and either gp91-PHOX (CYBB) or NOX1 produced superoxide. Cells individually transfected with NOX1, p41-NOX, or p51-NOX and cells transfected with only p41-NOX and p51-NOX showed no superoxide production.
Gene Full Name: NADPH oxidase activator 1
Sequence Similarities: Belongs to the NCF2/NOXA1 family.
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基因ID
- 10811
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UniProt
- Q86UR1
抗原
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