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STXBP1 抗体 (AA 11-110) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-STXBP1 antibody specifically detects STXBP1 in WB, ELISA, IHC (p) 和 IHC (fro). The antibody is reactive with 大鼠 samples.
产品编号 ABIN751665
发货至: 中国
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Quick Overview for STXBP1 抗体 (AA 11-110) (Biotin) (ABIN751665)

抗原

See all STXBP1 抗体
STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This STXBP1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 11-110

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Munc18

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

    别名

    STXBP1/Munc18

    背景

    Synonyms: Munc 18 1, Munc 18a, NSec1, p67, Rb sec1, STXBP1, Syntaxin binding protein 1, Unc 18 homolog, Unc 18A, Unc18 1, STXB1_HUMAN, Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67.

    Background: Munc18 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.Mutations in Munc18 can result in accumulations of acetylcholine and paralytic phenotype suggestive of a neurotransmitter release defect. Two Munc18 isoforms have recently been identified. Munc18-1 has been shown to be primarily expressed in brain, while Munc18-2 is expressed in most tissues.

    基因ID

    6812

    UniProt

    P61764

    途径

    Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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