NECAB3 抗体 (AA 97-339) (Fluoro550)
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北京 101111
Quick Overview for NECAB3 抗体 (AA 97-339) (Fluoro550) (ABIN8013264)
抗原
See all NECAB3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 97-339
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原理
- Anti-NECAB3 Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NECAB3 recombinant protein (Position: D97-D339).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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别名
- NECAB3
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背景
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Background: N-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: N-terminal EF-hand calcium binding protein 3
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基因ID
- 63941
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UniProt
- Q96P71
抗原
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