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NSF 抗体 (AA 620-744) (PE)

This 兔 多克隆 antibody specifically detects NSF in FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN8013137
发货至: 中国
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Quick Overview for NSF 抗体 (AA 620-744) (PE) (ABIN8013137)

抗原

See all NSF 抗体
NSF (N-Ethylmaleimide-Sensitive Factor (NSF))

适用

  • 73
  • 55
  • 55
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 84
  • 6
  • 1

克隆类型

  • 87
  • 4
多克隆

标记

  • 39
  • 7
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NSF antibody is conjugated to PE

应用范围

  • 63
  • 34
  • 18
  • 15
  • 13
  • 13
  • 10
  • 10
  • 8
  • 8
  • 3
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 620-744

    原理

    Anti-NSF Antibody PE Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human NSF recombinant protein (Position: N620-D744).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    NSF (N-Ethylmaleimide-Sensitive Factor (NSF))

    别名

    NSF

    背景

    Background: N-ethylmaleimide-sensitive factor, also known as NSF, is an enzyme which in humans is encoded by the NSF gene. NSF is a homohexameric AAA ATPase involved in membrane fusion. NSF is ubiquitously found in the cytoplasm of eukaryotic cells. It is a central component of the cellular machinery in the transfer of membrane vesicles from one membrane compartment to another. During this process, SNARE proteins on two joining membranes (usually a vesicle and a target membrane such as the plasma membrane) form a tight complex. This aids fusion of the vesicle with the target membrane. It has been proposed that the role of NSF is to undo these SNARE complexes once membrane fusion has occurred, using the hydrolysis of ATP as an energy source, allowing the dissociated SNAREs to be recycled for reuse in further rounds of membrane fusion. This proposal remains controversial, however. Recent work indicates that the ATPase function of NSF does not function in recycling of vesicles but rather functions in the act of fusing vesicles with the plasma membrane.

    Gene Full Name: N-ethylmaleimide sensitive factor, vesicle fusing ATPase

    基因ID

    10874

    UniProt

    P46459
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