NANS 抗体 (AA 1-341) (FITC)
Our Local Distributor
北京 101111
Quick Overview for NANS 抗体 (AA 1-341) (FITC) (ABIN8013012)
抗原
See all NANS 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-341
-
原理
- Anti-NANS Antibody FITC Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human NANS recombinant protein (Position: M1-E341). Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- NANS (N-Acetylneuraminic Acid Synthase (NANS))
-
别名
- NANS
-
背景
-
Background: Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Gene Full Name: N-acetylneuraminate synthase
-
基因ID
- 54187
-
UniProt
- Q9NR45
抗原
-