MYO1E 抗体 (AA 221-1065) (FITC)
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北京 101111
Quick Overview for MYO1E 抗体 (AA 221-1065) (FITC) (ABIN8012715)
抗原
See all MYO1E 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-1065
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原理
- Anti-MYO1E Antibody FITC Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human MYO1E shares 95.9%,95.3% amino acid (aa) sequence identity with mouse,rat MYO1E,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MYO1E recombinant protein (Position: A221-Q1065). Human MYO1E shares 95.9% and 95.3% amino acid (aa) sequence identity with mouse and rat MYO1E, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MYO1E (Myosin IE (MYO1E))
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别名
- MYO1E
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背景
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Background: This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.
Gene Full Name: myosin IE
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基因ID
- 4643
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UniProt
- Q12965
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途径
- Platelet-derived growth Factor Receptor Signaling
抗原
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