Myoferlin 抗体 (AA 175-2003) (Fluoro550)
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北京 101111
Quick Overview for Myoferlin 抗体 (AA 175-2003) (Fluoro550) (ABIN8012569)
抗原
See all Myoferlin (MYOF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 175-2003
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原理
- Anti-MYOF Antibody Fluoro550 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MYOF recombinant protein (Position: E175-E2003). Human MYOF shares 93.9% amino acid (aa) sequence identity with mouse MYOF.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Myoferlin (MYOF)
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别名
- MYOF
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背景
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Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
Gene Full Name: myoferlin
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基因ID
- 26509
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UniProt
- Q9NZM1
抗原
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