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MIOX 抗体 (AA 1-266) (PE)

The PE-conjugated 兔 多克隆 anti-MIOX antibody (ABIN8012530) specifically detects MIOX in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8012530
发货至: 中国
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Quick Overview for MIOX 抗体 (AA 1-266) (PE) (ABIN8012530)

抗原

See all MIOX 抗体
MIOX (Myo-Inositol Oxygenase (MIOX))

适用

人, 小鼠, 大鼠

宿主

  • 38
  • 5

克隆类型

  • 38
  • 5
多克隆

标记

  • 19
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MIOX antibody is conjugated to PE

应用范围

  • 26
  • 18
  • 16
  • 13
  • 5
  • 3
  • 2
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 9
    • 7
    • 2
    • 1
    AA 1-266

    原理

    Anti-MIOX Antibody PE Conjugated

    预测反应

    Human MIOX shares 89.8%,90.5% amino acid (aa) sequence identity with mouse,rat MIOX,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MIOX recombinant protein (Position: M1-K266). Human MIOX shares 89.8% and 90.5% amino acid (aa) sequence identity with mouse and rat MIOX, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MIOX (Myo-Inositol Oxygenase (MIOX))

    别名

    MIOX

    背景

    Background: Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91 % and 96 % sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the FeII/FeIII binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy.

    Gene Full Name: myo-inositol oxygenase

    基因ID

    55586

    UniProt

    Q9UGB7

    途径

    Inositol Metabolic Process
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