MIOX 抗体 (AA 1-266) (HRP)
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北京 101111
Quick Overview for MIOX 抗体 (AA 1-266) (HRP) (ABIN8012528)
抗原
See all MIOX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-266
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原理
- Anti-MIOX Antibody HRP Conjugated
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预测反应
- Human MIOX shares 89.8%,90.5% amino acid (aa) sequence identity with mouse,rat MIOX,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MIOX recombinant protein (Position: M1-K266). Human MIOX shares 89.8% and 90.5% amino acid (aa) sequence identity with mouse and rat MIOX, respectively.
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亚型
- IgG
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anti-Myo-Inositol Oxygenase (MIOX) (AA 1-285) antibody
MIOX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myo-Inositol Oxygenase (MIOX) (AA 1-30), (N-Term) antibodyMIOX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33052 unconjugated
anti-Myo-Inositol Oxygenase (MIOX) (AA 1-285) antibodyMIOX 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-Myo-Inositol Oxygenase (MIOX) antibodyMIOX 适用: 人 WB, IF, IHC 宿主: 小鼠 Monoclonal 5H10 unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- MIOX (Myo-Inositol Oxygenase (MIOX))
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别名
- MIOX
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背景
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Background: Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91 % and 96 % sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the FeII/FeIII binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy.
Gene Full Name: myo-inositol oxygenase
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基因ID
- 55586
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UniProt
- Q9UGB7
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途径
- Inositol Metabolic Process
抗原
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