Myeloperoxidase 抗体 (AA 406-745)
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Quick Overview for Myeloperoxidase 抗体 (AA 406-745) (ABIN8012510)
抗原
See all Myeloperoxidase (MPO) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 406-745
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原理
- Anti-Myeloperoxidase/MPO Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.
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产品特性
- Anti-Myeloperoxidase/MPO Antibody. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Myeloperoxidase recombinant protein (Position:S406-S745). Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Myeloperoxidase (MPO)
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别名
- MPO
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背景
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Background: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697 (A49-S745) amino acids with the molecular mass of 80KDa.
Gene Full Name: myeloperoxidase
Sequence Similarities: Belongs to the peroxidase family. XPO subfamily.
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分子量
- 60-65 kDa, 80-90 kDa
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基因ID
- 4353
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UniProt
- P05164
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途径
- Chromatin Binding
抗原
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