MAG 抗体 (N-Term) (Fluoro647)
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北京 101111
Quick Overview for MAG 抗体 (N-Term) (Fluoro647) (ABIN8012366)
抗原
See all MAG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-Myelin-associated glycoprotein MAG Antibody Fluoro647 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related rat,mouse sequences.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MAG, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-Myelin Associated Glycoprotein (MAG) (AA 439-466) antibody
MAG 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB21439 unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 133-237) antibodyMAG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 119-208) antibodyMAG 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 25-516) antibodyMAG 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 34-605) antibodyMAG 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal 2G11 unconjugated
anti-Myelin Associated Glycoprotein (MAG) antibodyKD Validated MAG 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2600 unconjugated Recombinant Antibody
anti-Myelin Associated Glycoprotein (MAG) antibodyMAG 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 501-582) antibodyMAG 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 551-626) antibodyMAG 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (N-Term) antibodyMAG 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MAG (Myelin Associated Glycoprotein (MAG))
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别名
- MAG
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背景
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Background: MAG (Myelin-associated glycoprotein),also known as SIGLEC4A, is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is though to be involved in the process of myelination. MAG is a sialic acid-binding SIGLEC protein and is a functional ligand for the NOGO receptor.The MAG gene is mapped on 19q13.12. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered MAG-sensitive by expression of NgR. MAG binds specifically to an NgR-expressing cell line in a GPI-dependent and sialic acid-independent manner. Experiments blocking NgR from interacting with MAG prevented inhibition of neurite outgrowth by MAG. In cultured human embryonic kidney (HEK) cells expressing the NOGO receptor, p75 (NTR) was required for MAG-induced intracellular calcium elevation.
Gene Full Name: myelin associated glycoprotein
Sequence Similarities: Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
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基因ID
- 4099
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UniProt
- P20916
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途径
- Neurotrophin Signaling Pathway
抗原
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