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Mps1 抗体 (AA 487-821) (HRP)

The HRP-conjugated 兔 多克隆 anti-Mps1 antibody (ABIN8011714) specifically detects Mps1 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8011714
发货至: 中国
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Quick Overview for Mps1 抗体 (AA 487-821) (HRP) (ABIN8011714)

抗原

See all Mps1 (TTK) 抗体
Mps1 (TTK)

适用

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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 77
  • 10
  • 1

克隆类型

  • 79
  • 9
多克隆

标记

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  • 6
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  • 3
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  • 1
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This Mps1 antibody is conjugated to HRP

应用范围

  • 59
  • 41
  • 28
  • 13
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  • 11
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  • 8
  • 3
  • 2
  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 12
    • 10
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 487-821

    原理

    Anti-TTK/Mps1/TTK Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TTK/Mps1/TTK recombinant protein (Position: Q487-S821).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Mps1 (TTK)

    别名

    TTK

    背景

    Background: Dual specificity protein kinase TTK is a protein that in humans is encoded by the XRCC2 gene. This gene is mapped to 6q14.1. This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.

    Gene Full Name: TTK protein kinase

    基因ID

    7272

    UniProt

    P33981
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