Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (AA 10-459) 抗体 (Biotin)
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Quick Overview for Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (AA 10-459) 抗体 (Biotin) (ABIN8010795)
抗原
See all Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-459
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原理
- Anti-MT-ND4 Antibody Biotin Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MT-ND4 recombinant protein (Position: M10-S459).
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亚型
- IgG
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anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) antibody
MT-ND4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (AA 350-450) antibodyMT-ND4 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (AA 406-459) antibodyMT-ND4 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (N-Term) antibodyMT-ND4 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (AA 10-459) antibodyMT-ND4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4)
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别名
- MT-ND4
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背景
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Background: NADH-ubiquinone oxidoreductase chain 4 is a protein that in humans is encoded by the mitochondrial gene MT-ND4. MT-ND4 is a subunit of the respiratory chain Complex I that is believed to belong to the minimal assembly of core proteins required to catalyze NADH dehydrogenation and electron transfer to ubiquinone (coenzyme Q10). Initially, NADH binds to Complex I and transfers two electrons to the isoalloxazine ring of the flavin mononucleotide (FMN) prosthetic arm to form FMNH2. The electrons are transferred through a series of iron-sulfur (Fe-S) clusters in the prosthetic arm and finally to coenzyme Q10 (CoQ), which is reduced to ubiquinol (CoQH2). The flow of electrons changes the redox state of the protein, resulting in a conformational change and pK shift of the ionizable side chain, which pumps four hydrogen ions out of the mitochondrial matrix.
Gene Full Name: NADH dehydrogenase subunit 4
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基因ID
- 4538
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UniProt
- P03905
抗原
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