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MFGE8 抗体 (AA 24-387)

The 兔 多克隆 anti-MFGE8 antibody (ABIN8010244) specifically detects MFGE8 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN8010244
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MFGE8 抗体 (AA 24-387) (ABIN8010244)

抗原

See all MFGE8 抗体
MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

适用

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宿主

  • 98
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克隆类型

  • 102
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多克隆

标记

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This MFGE8 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

质量等级

Carrier-free
  • 抗原表位

    • 23
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    AA 24-387

    原理

    Anti-Milk Fat Globule 1/MFGE8 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Milk Fat Globule 1/MFGE8 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Milk Fat Globule 1/MFGE8 recombinant protein (Position: L24-C387).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

    别名

    MFGE8

    背景

    Background: MFGE8(Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism.

    Gene Full Name: milk fat globule EGF and factor V/VIII domain containing

    分子量

    43 kDa

    基因ID

    4240

    UniProt

    Q08431

    途径

    SARS-CoV-2 Protein Interactome
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