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MFGE8 抗体 (Middle Region) (FITC)

The 兔 多克隆 anti-MFGE8 antibody is suitable to detect MFGE8 in samples from 人. It has been validated for FACS.
产品编号 ABIN8010228
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for MFGE8 抗体 (Middle Region) (FITC) (ABIN8010228)

抗原

See all MFGE8 抗体
MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

适用

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宿主

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克隆类型

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多克隆

标记

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This MFGE8 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    Middle Region

    原理

    Anti-Milk Fat Globule 1/MFGE8 Antibody FITC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human Milk Fat Globule 1/MFGE8, which shares 70.6% amino acid (aa) sequence identity with mouse and rat MFGE8.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

    别名

    MFGE8

    背景

    Background: MFGE8(Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism.

    Gene Full Name: milk fat globule EGF and factor V/VIII domain containing

    基因ID

    4240

    UniProt

    Q08431

    途径

    SARS-CoV-2 Protein Interactome
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