MFAP3 抗体 (AA 19-349) (Biotin)
Our Local Distributor
北京 101111
Quick Overview for MFAP3 抗体 (AA 19-349) (Biotin) (ABIN8009958)
抗原
See all MFAP3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 19-349
-
原理
- Anti-MFAP3 Antibody Biotin Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human MFAP3 recombinant protein (Position: A19-N349).
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- MFAP3 (Microfibrillar Associated Protein 3 (MFAP3))
-
别名
- MFAP3
-
背景
-
Background: Microfibril-associated glycoprotein 3 (MFAP3), is a member of the MFAP family which play a role in microfibril assembly, elastinogenesis, and tissue homeostasis. The family members were identified as potential components of fibrillin-containing microfibrils, but they do not share structural similarities. MFAP3 is found in ocular zonules. Human MFAP3 is a serine-rich acidic protein located in zonular fibers and consists of an extracellular domain (ECD) containing one Ig-like C2-type domain, a single transmembrane domain, and a cytoplasmic domain. Within the ECD, mature human MFAP3 shares 74 % amino acid sequence identity with mouse and rat MFAP3. Among MFAP3-related pathways are degradation of the extracellular matrix and elastic fiber formation. MFAP is a candidate gene for heritable diseases affecting microfibrils.
Gene Full Name: microfibril associated protein 3
-
基因ID
- 4238
-
UniProt
- P55082
抗原
-