MVK 抗体 (AA 13-394) (HRP)
Our Local Distributor
北京 101111
Quick Overview for MVK 抗体 (AA 13-394) (HRP) (ABIN8009876)
抗原
See all MVK 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 13-394
-
原理
- Anti-MVK Antibody HRP Conjugated
-
预测反应
- Human MVK shares 80.8%,81.4% amino acid (aa) sequence identity with mouse,rat MVK,respectively.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human MVK recombinant protein (Position: K13-D394). Human MVK shares 80.8% and 81.4% amino acid (aa) sequence identity with mouse and rat MVK, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- MVK (Mevalonate Kinase (MVK))
-
别名
- MVK
-
背景
-
Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants.
Gene Full Name: mevalonate kinase
-
基因ID
- 4598
-
UniProt
- Q03426
抗原
-