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MVK 抗体 (AA 13-394) (HRP)

This 兔 多克隆 antibody specifically detects MVK in WB, ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN8009876
发货至: 中国
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Quick Overview for MVK 抗体 (AA 13-394) (HRP) (ABIN8009876)

抗原

See all MVK 抗体
MVK (Mevalonate Kinase (MVK))

适用

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宿主

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克隆类型

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多克隆

标记

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This MVK antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 13-394

    原理

    Anti-MVK Antibody HRP Conjugated

    预测反应

    Human MVK shares 80.8%,81.4% amino acid (aa) sequence identity with mouse,rat MVK,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MVK recombinant protein (Position: K13-D394). Human MVK shares 80.8% and 81.4% amino acid (aa) sequence identity with mouse and rat MVK, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MVK (Mevalonate Kinase (MVK))

    别名

    MVK

    背景

    Background: This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants.

    Gene Full Name: mevalonate kinase

    基因ID

    4598

    UniProt

    Q03426
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