MESDC2 抗体 (AA 80-205) (HRP)
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Quick Overview for MESDC2 抗体 (AA 80-205) (HRP) (ABIN8009194)
抗原
See all MESDC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-205
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原理
- Anti-MESDC2/MESD Antibody HRP Conjugated
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MESDC2/MESD recombinant protein (Position: D80-Q205).
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亚型
- IgG
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anti-Mesoderm Development Candidate 2 (MESDC2) (AA 1-234) antibody
MESDC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) antibodyMESDC2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (Internal Region) antibodyMESDC2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (AA 1-234) antibodyMESDC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (AA 203-234), (C-Term) antibodyMESDC2 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Mesoderm Development Candidate 2 (MESDC2) (AA 80-205) antibodyMESDC2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- MESDC2 (Mesoderm Development Candidate 2 (MESDC2))
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别名
- MESD
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背景
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Background: Mesoderm development candidate genes 1 (MESDC1) and 2 (MESDC2) were identified from the mesoderm development (MESD) deletion interval located on mouse chromosome 7. MESD acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6. MESD is required for proper LRP5/6 folding and maturation to the cell surface, which plays a major role in Wnt signaling. The interaction between MESD and LRP5 is disrupted by a G171V mutation in LRP5 that is found in individuals with a familial phenotype characterized by high bone mass.
Gene Full Name: mesoderm development LRP chaperone
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基因ID
- 23184
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UniProt
- Q14696
抗原
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