Meprin B 抗体 (AA 73-489) (HRP)
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Quick Overview for Meprin B 抗体 (AA 73-489) (HRP) (ABIN8009150)
抗原
See all Meprin B (MEP1B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 73-489
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原理
- Anti-MEP1B Antibody HRP Conjugated
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预测反应
- Human MEP1B shares 82.3%,81.5% amino acid (aa) sequence identity with mouse,rat MEP1B,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MEP1B recombinant protein (Position: H73-Q489). Human MEP1B shares 82.3% and 81.5% amino acid (aa) sequence identity with mouse and rat MEP1B, respectively.
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亚型
- IgG
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anti-Meprin A, beta (MEP1B) (AA 433-679) antibody
MEP1B 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Meprin A, beta (MEP1B) (AA 480-652) antibodyMEP1B 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Meprin A, beta (MEP1B) (AA 432-676) antibodyMEP1B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Meprin B (MEP1B) (Meprin A, beta (MEP1B))
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别名
- MEP1B
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背景
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Background: Meprin A subunit beta is a protein that in humans is encoded by the MEP1B gene. Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
Gene Full Name: meprin A subunit beta
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基因ID
- 4225
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UniProt
- Q16820
抗原
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