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Melanophilin 抗体 (AA 61-523) (HRP)

The HRP-conjugated 兔 多克隆 anti-Melanophilin antibody (ABIN8008963) specifically detects Melanophilin in WB, ELISA 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN8008963
发货至: 中国
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Quick Overview for Melanophilin 抗体 (AA 61-523) (HRP) (ABIN8008963)

抗原

See all Melanophilin (MLPH) 抗体
Melanophilin (MLPH)

适用

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宿主

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克隆类型

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多克隆

标记

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This Melanophilin antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 61-523

    原理

    Anti-MLPH Antibody HRP Conjugated

    预测反应

    Human Melanophilin,MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin,MLPH.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Melanophilin/MLPH recombinant protein (Position: E61-L523). Human Melanophilin/MLPH shares 61.6% amino acid (aa) sequence identity with mouse Melanophilin/MLPH.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Melanophilin (MLPH)

    别名

    MLPH

    背景

    Background: Melanophilin is a carrier protein which in humans is encoded by the MLPH gene. This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: melanophilin

    基因ID

    79083

    UniProt

    Q9BV36
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