MATK 抗体 (AA 18-298) (Fluoro488)
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Quick Overview for MATK 抗体 (AA 18-298) (Fluoro488) (ABIN8008783)
抗原
See all MATK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-298
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原理
- Anti-MATK Antibody Fluoro488 Conjugated
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预测反应
- Human MATK shares 88.5%,91.4% amino acid (aa) sequence identity with mouse,rat MATK,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MATK recombinant protein (Position: S18-Q298). Human MATK shares 88.5% and 91.4% amino acid (aa) sequence identity with mouse and rat MATK, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
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别名
- MATK
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背景
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Background: Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene. The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Gene Full Name: megakaryocyte-associated tyrosine kinase
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基因ID
- 4145
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UniProt
- P42679
抗原
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