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MEFV 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects MEFV in WB. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN8008736
发货至: 中国
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Room 801-803
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Quick Overview for MEFV 抗体 (N-Term) (ABIN8008736)

抗原

See all MEFV 抗体
MEFV (Mediterranean Fever (MEFV))

适用

  • 46
  • 16
  • 12
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 43
  • 2
  • 1

克隆类型

  • 45
  • 1
多克隆

标记

  • 18
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
This MEFV antibody is un-conjugated

应用范围

  • 25
  • 22
  • 20
  • 7
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB)

质量等级

Carrier-free
  • 抗原表位

    • 15
    • 13
    • 7
    • 4
    • 2
    • 1
    • 1
    N-Term

    原理

    Anti-MEFV Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse sequence by eight amino acids,and from the related rat sequence by eleven amino acids.

    产品特性

    Anti-MEFV Antibody. Tested in WB applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human MEFV, different from the related mouse sequence by eight amino acids, and from the related rat sequence by eleven amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MEFV (Mediterranean Fever (MEFV))

    别名

    MEFV

    背景

    Background: MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with thecytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response. Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. And Pyrin may the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.

    Gene Full Name: MEFV innate immunity regulator, pyrin

    分子量

    86 kDa

    基因ID

    4210

    UniProt

    O15553

    途径

    Positive Regulation of Endopeptidase Activity
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