MED12 抗体 (AA 752-1974)
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北京 101111
Quick Overview for MED12 抗体 (AA 752-1974) (ABIN8008538)
抗原
See all MED12 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 752-1974
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原理
- Anti-MED12 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MED12 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MED12 recombinant protein (Position: Q752-Q1974).
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亚型
- IgG
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anti-Mediator Complex Subunit 12 (MED12) (AA 2127-2177) antibody
MED12 适用: 人, 小鼠 IHC, WB, FACS, IP, ICC 宿主: 兔 Monoclonal BLR084G unconjugated Recombinant Antibody
anti-Mediator Complex Subunit 12 (MED12) (AA 1991-2025), (C-Term) antibodyMED12 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB52354 unconjugated
anti-Mediator Complex Subunit 12 (MED12) (C-Term) antibodyMED12 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 1829-1941) antibodyMED12 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 1742-2011) antibodyMED12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) antibodyMED12 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (C-Term) antibodyMED12 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 12 (MED12) (AA 251-350) antibodyMED12 适用: 小鼠, 大鼠 ELISA, WB, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- MED12 (Mediator Complex Subunit 12 (MED12))
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别名
- MED12
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背景
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Background: Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae), also known as MED12, is a human gene found on the X chromosome. The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome.
Gene Full Name: mediator complex subunit 12
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分子量
- 260 kDa
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基因ID
- 9968
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UniProt
- Q93074
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
抗原
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