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MXD1 抗体 (AA 1-221) (APC)

The APC-conjugated 兔 多克隆 anti-MXD1 antibody (ABIN8008348) specifically detects MXD1 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8008348
发货至: 中国
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Quick Overview for MXD1 抗体 (AA 1-221) (APC) (ABIN8008348)

抗原

See all MXD1 抗体
MXD1 (MAX Dimerization Protein 1 (MXD1))

适用

  • 33
  • 18
  • 17
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 32
  • 3

克隆类型

  • 32
  • 3
多克隆

标记

  • 21
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MXD1 antibody is conjugated to APC

应用范围

  • 25
  • 16
  • 7
  • 3
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 12
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-221

    原理

    Anti-Mad/MXD1 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Mad recombinant protein (Position: M1-L221).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MXD1 (MAX Dimerization Protein 1 (MXD1))

    别名

    MXD1

    背景

    Background: MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Gene Full Name: MAX dimerization protein 1

    基因ID

    4084

    UniProt

    Q05195
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