MMP20 抗体 (AA 124-405) (Cy3)
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北京 101111
Quick Overview for MMP20 抗体 (AA 124-405) (Cy3) (ABIN8008331)
抗原
See all MMP20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-405
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原理
- Anti-MMP20 Antibody Cy3 Conjugated
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交叉反应 (详细)
- No cross reactivity with other proteins.
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预测反应
- Human MMP20 shares 91.5% amino acid (aa) sequence identity with mouse MMP20.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MMP20 recombinant protein (Position: Y124-K405). Human MMP20 shares 91.5% amino acid (aa) sequence identity with mouse MMP20.
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MMP20 (Matrix Metalloproteinase 20 (MMP20))
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别名
- MMP20
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背景
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Background: Matrix metalloproteinase-20 (MMP-20) also known as enamel metalloproteinase or enamelysin is an enzyme that in humans is encoded by the MMP20 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3.
Gene Full Name: matrix metallopeptidase 20
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基因ID
- 9313
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UniProt
- O60882
抗原
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