MMP8 抗体 (N-Term) (HRP)
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北京 101111
Quick Overview for MMP8 抗体 (N-Term) (HRP) (ABIN8008237)
抗原
See all MMP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-MMP8 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related mouse sequence by eleven amino acids.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MMP-8, different from the related mouse sequence by eleven amino acids.
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亚型
- IgG
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anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 101-467) antibody
MMP8 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) antibodyMMP8 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) antibodyMMP8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 241-340) antibodyMMP8 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (N-Term) antibodyMMP8 适用: 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 1-467) antibodyMMP8 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 1-467) antibodyMMP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (C-Term) antibodyMMP8 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 286-315) antibodyMMP8 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2017-2018 unconjugated
anti-Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8) (AA 22-283) antibodyMMP8 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
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别名
- MMP8
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背景
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Background: MMP8 (Matrix metalloproteinase 8) is a member of the family of matrix metalloproteinases. It is distinct from the collagenase of skin fibroblasts and synovial cells in substrate specificity and immunologic crossreactivity. MMP8 is mapped to 11q21-q22. MMP8 is an enzyme that degrades fibrillar collagens imparting strength to the fetal membranes, is expressed by leukocytes and chorionic cytotrophoblast cells. The enzyme exhibits 58 % homology to human fibroblast collagenase and has the same domain structure. It consists of a 20-residue signal peptide, and an 80-residue propeptide that is lost on autolytic activation by cleavage of an M-L bond. MMP8 was found to possess 57 % identity with the deduced protein sequence for fibroblast collagenase with 72 % chemical similarity. Matrix metalloproteinases (MMPs) have fundamental roles in tumor progression, but most clinical trials with MMP inhibitors have not shown improvements in individuals with cancer. MMP8 has a paradoxical protective role in cancer and provides a genetic model to evaluate the molecular basis of gender differences in cancer susceptibility.
Gene Full Name: matrix metallopeptidase 8
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基因ID
- 4317
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UniProt
- P22894
抗原
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