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MMP24 抗体 (N-Term) (HRP)

The 兔 多克隆 anti-MMP24 antibody is suitable to detect MMP24 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN8008182
发货至: 中国
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Quick Overview for MMP24 抗体 (N-Term) (HRP) (ABIN8008182)

抗原

See all MMP24 抗体
MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

适用

  • 38
  • 26
  • 25
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  • 2
  • 2
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  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 38
  • 1

克隆类型

  • 38
  • 1
多克隆

标记

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  • 3
  • 2
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  • 1
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This MMP24 antibody is conjugated to HRP

应用范围

  • 21
  • 10
  • 10
  • 9
  • 6
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 12
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    Anti-Matrix metalloproteinase-24 MMP24 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human MMP24, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

    别名

    MMP24

    背景

    Background: Matrix metalloproteinase-24, also known as MT5MMP or MMP25, is an enzyme that in humans is encoded by the MMP24 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. This gene may be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans.

    Gene Full Name: matrix metallopeptidase 24

    Sequence Similarities: Belongs to the peptidase M10A family.

    基因ID

    10893

    UniProt

    Q9Y5R2
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