MADD 抗体 (AA 5-329) (FITC)
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Quick Overview for MADD 抗体 (AA 5-329) (FITC) (ABIN8007807)
抗原
See all MADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-329
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原理
- Anti-MADD Antibody FITC Conjugated
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MADD recombinant protein (Position: K5-Y329).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- MADD (MAP-Kinase Activating Death Domain (MADD))
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别名
- MADD
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背景
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Background: MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.
Gene Full Name: MAP kinase activating death domain
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基因ID
- 8567
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UniProt
- Q8WXG6
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途径
- Caspase Cascade in Apoptosis
抗原
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