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MADD 抗体 (AA 5-329) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-MADD antibody (ABIN8007805) specifically detects MADD in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN8007805
发货至: 中国
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Quick Overview for MADD 抗体 (AA 5-329) (Fluoro550) (ABIN8007805)

抗原

See all MADD 抗体
MADD (MAP-Kinase Activating Death Domain (MADD))

适用

  • 54
  • 48
  • 39
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 66

克隆类型

  • 53
  • 13
多克隆

标记

  • 27
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MADD antibody is conjugated to Fluoro550

应用范围

  • 35
  • 22
  • 15
  • 14
  • 13
  • 11
  • 8
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 5-329

    原理

    Anti-MADD Antibody Fluoro550 Conjugated

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MADD recombinant protein (Position: K5-Y329).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    MADD (MAP-Kinase Activating Death Domain (MADD))

    别名

    MADD

    背景

    Background: MAP kinase-activating death domain protein is an enzyme that in humans is encoded by the MADD gene. Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene.

    Gene Full Name: MAP kinase activating death domain

    基因ID

    8567

    UniProt

    Q8WXG6

    途径

    Caspase Cascade in Apoptosis
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