Macro H2A.2 (AA 181-340) 抗体 (Biotin)
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Quick Overview for Macro H2A.2 (AA 181-340) 抗体 (Biotin) (ABIN8007197)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-340
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原理
- Anti-H2AFY2/MACROH2A2 Antibody Biotin Conjugated
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交叉反应 （详细）
- No cross reactivity with other proteins.
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预测反应
- Human MACROH2A2 shares 99.4% amino acid (aa) sequence identity with mouse MACROH2A2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human H2AFY2/MACROH2A2 recombinant protein (Position: D181-D340). Human MACROH2A2 shares 99.4% amino acid (aa) sequence identity with mouse MACROH2A2.
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亚型
- IgG
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anti-Macro H2A.2 (C-Term) antibody
适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- Macro H2A.2
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别名
- MACROH2A2
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背景
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Background: Core histone macro-H2A.2 is a protein that in humans is encoded by the H2AFY2 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and may participate in stable X chromosome inactivation.
Gene Full Name: macroH2A.2 histone
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基因ID
- 55506
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UniProt
- Q9P0M6
抗原
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